Resin-free oligonucleotide purification

GemBio's ClarityCapture™ and ClarityCapture™ Plus purification technologies replace traditional column based purification using a proprietary cleavable tag. This tag enables selective capture of therapeutic oligos without requiring solid phase resin or large solvent volumes.

ClarityCapture™ is compatible with standard phosphoramidite synthesis workflows and preserves the full flexibility of the drug developer’s chemical toolkit across existing and next generation modifications.
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